Drug overdose deaths continue to increase in the United States.

  • From 1999 to 2016, more than 630,000 people have died from a drug overdose.
  • Around 66% of the more than 63,600 drug overdose deaths in 2016 involved an opioid.
  • In 2016, the number of overdose deaths involving opioids (including prescription opioids and illegal opioids like heroin and illicitly manufactured fentanyl) was 5 times higher than in 1999.
  • On average, 115 Americans die every day from an opioid overdose.1